The macrophage chemotactic activity of Edwardsiella tarda extracellular products.

Extracellular products from virulent strain of Edwardsiella tarda stimulate mouse macrophages (RAW264.7) to produce nitric oxide (NO) and tumor necrosis factor (TNF)-

Intramacrophage Infection Reinforces the Virulence of Edwardsiella tarda.

UNLABELLED Edwardsiella tarda is an important pathogenic bacterium that can replicate in macrophages. However, how the intramacrophage infection process affects the virulence of this bacterium is essentially unknown. Here, we show that E. tarda replicates and induces a caspase-1-dependent cell pyroptosis in a murine macrophage model. Via pyroptosis, intracellular E. tarda escapes to the extrace...

Profile and protective role of 61kDa and 47kDa antigens of Edwardsiella tarda in rohu (Labeo rohita)

Edwardsiella tarda is a versatile pathogen that could survive in different environmental conditions and infect economically important fish species. The whole cell antigenic proteins were extracted from E. tarda and assessed via Western blot using anti E. trada rohu and anti E. trada rabbit serum. Two strong reacted proteins with antibodies were recovered viz 61 kDa and 47 kDa from SDS PAGE gels...

Extracellular products from virulent strain of Edwardsiella tarda stimulate mouse macrophages (RAW264.7) to produce nitric oxide (NO) and tumor necrosis factor (TNF)-alpha.

We have previously found that high virulent strain (NUF251) of Edwardsiella tarda, but not low virulent strain (NUF194), was able to survive and multiply within Japanese flounder (Paralichthys olivaceus) peritoneal macrophages. Further studies demonstrated that NUF251 induced much higher levels of NO and TNF-alpha productions than NUF194 in both Japanese flounder peritoneal macrophages and mous...

Effects of dietary supplementation of garlic (Allium sativum) extract on the resistance of Clarias gariepinus against Edwardsiella tarda infection

The effects of dietary supplementation of garlic (Allium sativum) extract on the growth and disease resistance of African catfish, Clarias gariepinus was evaluated. Also in-vitro evaluation of susceptibility of fish-borne multidrug resistant (MDR) pathogenic bacteria to aqueous extract of garlic was done. Aqueous garlic extract exhibited inhibitory activity against MDR bacteria and the degree o...